This section provides a comprehensive overview of the topic.
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:0020003 | internal globus pallidus core projecting neuron |
Nucleus Accumbens Core (Naccore) Expanded is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. [1]
The Nucleus Accumbens Core (NAcCore) is the central region of the ventral striatum, a key structure in the brain's reward and motivation circuitry. As part of the mesolimbic dopamine system, the NAcCore plays a fundamental role in reward processing, reinforcement learning, goal-directed behavior, and the integration of emotional and cognitive functions. [2]
](/mechanisms/mesolimbic-pathway)## Background
The study of Nucleus Accumbens Core (Naccore) Expanded has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development. [3]
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions. [4]
Additional evidence sources: [5] [6] [7]
Ikemoto S, et al. Functional organization of the nucleus accumbens. 2019. ↩︎
Koob GF, Volkow ND. Neurobiology of addiction: a circuit disorder. 2021. ↩︎
Zhang R, et al. Dopamine signaling in the nucleus accumbens. 2022. ↩︎
Russo SJ, Nestler EJ. The brain reward circuitry in mood disorders. 2019. ↩︎
Yager LM, et al. The nucleus accumbens: mechanisms of addiction. 2021. ↩︎
Sesack SR, Grace AA. Cortico-striatal circuitry in addiction. 2020. ↩︎
Carlezon WA, et al. Nucleus accumbens manipulations. 2021. ↩︎