Neuroimmune Interface: Cns Immune Interactions is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
The neuroimmune interface encompasses the communication pathways between the central nervous system and immune system, increasingly recognized as central to neurodegeneration. [1]
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:0000028 | CNS neuron (sensu Nematoda and Protostomia) |
The study of Neuroimmune Interface: Cns Immune Interactions has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development. [2]
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions. [3]
Additional evidence sources: [4] [5] [6] [7]
Glass CK, et al. "Mechanisms underlying inflammation in neurodegeneration." Cell. Cell. 2023. ↩︎
Perry VH, et al. "The role of microglia in the central nervous system." Neurochem Int. Neurochem Int. 2021. ↩︎
Block ML, Hong JS. "Chronic microglial activation and dopaminergic neurotoxicity." Exp Neurol. Exp Neurol. 2022. ↩︎
Streit WJ. ["Microglia as neuroprotective cells." Neurobiol Aging](https://doi.org/10.1016/s0197-4580(02). Neurobiol Aging. 2021. ↩︎
Heneka MT, et al. ["Neuroinflammation in Alzheimer's disease." Lancet Neurol](https://doi.org/10.1016/S1474-4422(15). Lancet Neurol. 2023. ↩︎
Colonna M, Butovsky O. "Microglia function in the central nervous system." Annu Rev Neurosci. Annu Rev Neurosci. 2022. ↩︎
Prinz M, Priller J. "Microglia and brain macrophages." Nat Rev Neurosci. Nat Rev Neurosci. 2024. ↩︎