Mesolimbic Dopaminergic Circuit is an important component in the neurobiology of neurodegenerative . This page provides detailed information about its structure, function, and role in disease processes.
The mesolimbic pathway projects from ventral tegmental area to limbic structures, mediating reward, motivation, and emotional processing. [1]
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:0000700 | dopaminergic neuron |
| Database | ID | Name | Confidence | [2]
|----------|----|------|------------| [3]
| Cell Ontology | CL:0000700 | dopaminergic neuron | Medium | [4]
](//vta-dopamine-neurons
The study of Mesolimbic Dopaminergic Circuit has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying of neurodegeneration and continues to drive therapeutic development. [5]
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions. [6]
Ikemoto S, Bonci A. "Neurocircuitry of drug reward." Neuropharmacology. Neuropharmacology. 2023. ↩︎
Nestler EJ. "Mesolimbic dopamine and reward." Mol Psychiatry. Mol Psychiatry. 2022. ↩︎
Wu J, et al. "Ventral tegmental area dopamine neuron plasticity." Neuropharmacology. Neuropharmacology. 2023. ↩︎
Lüscher C, Malenka RC. "Drug-evoked synaptic plasticity in the ventral tegmental area." Neuron. Neuron. 2021. ↩︎
Di Chiara G. "A motivational learning hypothesis of drug addiction." Adv Pharmacol. Adv Pharmacol. 2022. ↩︎
Berridge KC. "The debate over dopamine's role in reward." Hum Brain Mapp. Hum Brain Mapp. 2024. ↩︎