MCH neurons are hypothalamic neurons involved in energy homeostasis and sleep.
| Property |
Value |
| Category |
Neuropeptide Neurons |
| Location |
Lateral Hypothalamus |
| Cell Type |
MCH neurons |
| Neuropeptide |
MCH |
- PMCH: Pro-melanin concentrating hormone gene
- MCHR1: MCH receptor 1
- MCHR2: MCH receptor 2 (humans)
- Soma: Small to medium
- Dendrites: Extensively branched
- Projections: Widespread forebrain
- Food intake: MCH promotes feeding
- Metabolism: Energy expenditure
- Leptin interaction: Opposing effects
- REM sleep: MCH active during REM
- Sleep promotion: MCH induces sleep
- Narcolepsy: MCH system interactions
- MCH overexpression: Weight gain
- MCH antagonists: Potential treatment
- Metabolic syndrome: MCH role
- MCH in mood: Anxiogenic effects
- Stress response: MCH modulation
- Therapeutic target: MCH1 antagonists
- Bittencourt. MCH anatomy (1992)
- Nahon. MCH in energy balance (2006)