Lysosomal System In Neurons is an important component in the neurobiology of neurodegenerative . This page provides detailed information about its structure, function, and role in disease processes.
The lysosomal-autophagy system is essential for neuronal protein quality control and cellular homeostasis. Dysfunction is a central mechanism in neurodegenerative . [1]
Components: [2]
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:4042028 | immature neuron |
](//mitophagy-pathway
The study of Lysosomal System In Neurons has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying of neurodegeneration and continues to drive therapeutic development. [3]
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions. [4]
Additional evidence sources: [5] [6] [7]
Nixon RA. "The role of autophagy in neurodegenerative disease." Nat Med. Nat Med. 2023. ↩︎
Kisiswa L, et al. "Neuronal lysosomal dysfunction." Cell Death Differ. Cell Death Differ. 2021. ↩︎
Settembre C, et al. "Lysosomal storage ." Nat Rev Dis Primers. Nat Rev Dis Primers. 2023. ↩︎
Yue Z. "Regulation of neuronal autophagy in Parkinson's disease." Autophagy. Autophagy. 2022. ↩︎
Boland B, et al. "Autophagy and lysosomal dysfunction." J Neurosci. J Neurosci. 2023. ↩︎
Wolfe DM, et al. "Autophagy failure in Alzheimer's disease." Mol Neurodegener. Mol Neurodegener. 2021. ↩︎
Frake RA, et al. "Autophagy and neurodegeneration." J Clin Invest. J Clin Invest. 2022. ↩︎