Glutamatergic neurons use glutamate as their primary excitatory neurotransmitter. These neurons constitute approximately 70-80% of cortical neurons and are responsible for the vast majority of excitatory signaling in the brain.
Glutamate is the main excitatory neurotransmitter in the brain. Glutamatergic neurons: [1]
| Database | ID | Name | Confidence | [2]
|----------|----|------|------------|
| Cell Ontology | CL:0000679 | glutamatergic neuron | Exact |
| Cell Ontology | CL:2000028 | cerebellum glutamatergic neuron | Exact |
| Cell Ontology | CL:4300029 | cerebellar glutamatergic neuron (Mmus) | Exact |
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:0000679 | glutamatergic neuron |
The principal excitatory neurons of the cortex:
Dysfunction of glutamatergic signaling is implicated in:
](/cell-types/thalamocortical-neurons)## External Links
Mayer, NMDA receptors and Alzheimer's disease (2011). 2011. ↩︎
Vanhoutte et al. Glutamatergic neurons in neurodegeneration (2019). 2019. ↩︎