Dorsal Raphe Gabaergic Interneurons is an important cell type in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
The Dorsal Raphe Nucleus (DRN) contains not only serotonergic neurons but also a significant population of GABAergic interneurons that modulate serotonin release and raphe circuit function. [1]
GABAergic neurons in the dorsal raphe constitute approximately 20-30% of the local neuronal population. These interneurons provide inhibitory control over serotonergic neurons and play crucial roles in regulating mood, arousal, and reward processing. [2]
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:0000617 | GABAergic neuron |
| Database | ID | Name | Confidence |
|---|---|---|---|
| Cell Ontology | CL:0000617 | GABAergic neuron | Medium |
Calvo et al. GABAergic modulation of serotonergic neurons (2014). 2014. ↩︎
Huang et al. Raphe GABA in mood regulation (2019). 2019. ↩︎