Blood Brain Barrier Transport Cells is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
This page provides comprehensive information about the cell type. See the content below for detailed information. [1]
The blood-brain barrier (BBB) contains specialized transport systems that regulate the passage of nutrients, drugs, and waste products between the blood and brain. Dysfunction of these transporters is implicated in neurodegenerative diseases. [2]
| Database | ID | Name | Confidence |
|---|---|---|---|
| Cell Ontology | CL:0000081 | blood cell | Medium |
| Cell Ontology | CL:1001579 | cerebral cortex glial cell | Medium |
| Taxonomy | ID | Name / Label |
|---|---|---|
| Cell Ontology (CL) | CL:0000081 | blood cell |
| Nutrient | Transporter | Direction |
|---|---|---|
| Glucose | GLUT1 (SLC2A1) | Blood→Brain |
| Amino acids | LAT1 (SLC7A5) | Bidirectional |
| Nucleosides | CNT2 (SLC28A2) | Blood→Brain |
| Monocarboxylic acids | MCT1 (SLC16A1) | Bidirectional |
ABC Transporters (ATP-binding cassette):
Function: Pump drugs/toxins back to blood
Transport Changes:
The study of Blood Brain Barrier Transport Cells has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.